Horng H. Chen, M.D., is a board-certified cardiologist with subspecialty certification in heart failure and transplantation, adult comprehensive echocardiography and holds the academic rank of Professor of Medicine since 2011. He did his residency in Internal Medicine and his Cardiology Clinician Investigator Fellowship at Mayo Graduate School of Medicine, Mayo Clinic. Prior to coming on staff in 2001, Dr. Chen was a Mayo Foundation Scholar in the area of heart failure research.
Dr. Chen is a NIH-funded physician scientist who has advanced the field of Cardiorenal therapeutics in the area of heart failure. He is the Co-Director of the Cardiorenal Research Laboratory which is actively involved in research to uncover new therapies for heart failure and cardiorenal syndrome. Dr. Chen has been continuously funded by the NIH since 2005 and currently holds 2 NIH RO1 grants. He was elected to the prestigious American Society of Clinical Investigation in 2012.
Dr Chen is the Co-Director for Biological Agent and Drug Innovation, Dept of Cardiology at Mayo Clinic and the Co-Founder and Chief Medical Officer of Zumbro Discovery, a biotech company formed by Mayo Medical Ventures and Broadview Ventures. The goal of Zumbro Discovery is the clinical development of the novel peptide ZD 100 for the treatment of Resistant Hypertension. Dr Chen has been awarded 7 patents and has been involved in the clinical development of 2 other biotech companies.
He has over 115 publications and was the National Principal Investigator, leading a multicenter clinical trial performed within the NHLBI Heart Failure Clinical Research Network entitled: “The ROSE Study”. The Results if the study was presented as a late breaking clinical trial at AHA Scientific Session 2013 with simultaneous publication in JAMA.
Eddy Fan is an associate Professor in the Interdepartmental Division of Critical Care Medicine and the Institute of Health Policy, Management and Evaluation at the University of Toronto and a Staff Intensivist at the University Health Network/Mount Sinai Hospital. Dr. Fan received his undergraduate degree from the University of Toronto, his medical degree from the University of Western Ontario and a PhD in Clinical Investigation from Johns Hopkins University. He is currently the Medical Director of the Extracorporeal Life Support Program at the Toronto General Hospital, and the Director of Critical Care Research at the University Health Network/Mount Sinai Hospital. Dr. Fan’s research has focused on advanced life support for acute respiratory failure and patient outcomes from critical illness. These include investigations on the epidemiology and use of mechanical ventilation and extracorporeal life support in patients with ARDS, as well as on the development of ICU-acquired weakness, early rehabilitation in ICU patients, and long-term outcomes in survivors of critical illness.
Dr. Niall Ferguson is Head of Critical Care Medicine at the University Health Network and Sinai Health System, and full Professor in the Interdepartmental Division of Critical Care Medicine at the University of Toronto, with appointments in the Departments of Medicine and Physiology, and the Institute of Health Policy, Management and Evaluation at the University of Toronto. He is a Senior Scientist in the Toronto General Research Institute, and the Critical Care Lead for the Toronto-Central Local Health Integration Network. He received his M.D. with honours from the University of Toronto, and went on to complete post-graduate training in Internal Medicine, Respirology, and Critical Care Medicine. Dr. Ferguson completed a Master’s degree in Clinical Epidemiology and Health Care Research at the University of Toronto and subsequently undertook a CIHR Post-doctoral Fellowship in Madrid, Spain. He receives research funding from local, provincial, and national agencies, including the Canadian Institutes of Health Research. Dr. Ferguson’s research, which is published in high-impact journals including the New England Journal of Medicine, JAMA, and the American Journal of Respiratory & Critical Care Medicine focuses on: (1) mechanical ventilation (epidemiology; weaning and liberation; extubation and tracheostomy); (2) acute respiratory distress syndrome (definitions; ventilatory management; trial design); and (3) novel modes of mechanical ventilation, including extra-corporeal life support. Dr. Ferguson is the Scientific Programme Chair for Critical Care Canada Forum, Canada’s premier critical care conference. He is a frequent invited-speaker at national and international meetings, having given over 300 such talks.
Professor of Paediatric Tropical Infectious Diseases at the Faculty of Medicine and Director of the ICCARE Centre at the Institute for Global Health Innovation, Imperial College, London and an Honorary Fellow at MRC Clinical Trials Unit, University College, London.
Over the last 18 years, I have been based full-time in East Africa, where I lead a research group that have highlighted the unique importance of emergency-care research, previously poorly appreciated as an area for specific funder or policy investment, as a highly targeted and cost-effective means of tackling childhood mortality in resource-limited hospitals in sub-Saharan Africa. My major research portfolio includes severe malaria, bacterial sepsis and severe malnutrition and large Phase III pragmatic clinical trials in emergency care. My team conducted the largest trial in critically children ever undertaken in Africa (FEAST trial) examining fluid resuscitation strategies in children with severe febrile illness, showing that fluid boluses increased mortality compared to no-bolus (control). This went on to win the prestigious BMJ Research Paper of the Year award and led to changes in management guidelines.
David Krishna Menon is Professor and Head of the Division of Anaesthesia, and Professorial Fellow in Medicine at Queens’ College, Cambridge. He is Principal Investigator at the Wolfson Brain Imaging Centre and at the John van Geest Centre for Brain Repair in Cambridge, and Co-Chairs the Acute Brain Injury Program at the University of Cambridge. He is Chair of the European Brain Trauma Consortium and serves on the Executive of the International Neuro Trauma Society. He currently acts as Vice-Coordinator of the CENTER-TBI project, a €30 million FP7 European multicentre study of precision medicine and comparative effectiveness research in traumatic brain injury, and as Joint Director of the Cambridge NIHR Global Health Research Group on Neurotrauma. He has over a three hundred publications in peer reviewed journals, with a ‘h’ index of over 60, has contributed to major textbooks, and is one of two lead authors on a Commissioned Issue of the Lancet Neurology on Traumatic Brain Injury which was released at the European Parliament on the 7th of November 2017, and which has been used as a basis for briefing UK MPs in the All Party Parliamentary Group on Acquired Brain Injury.